abstract：PURPOSE:To determine the effect of routine use of prophylactic oral acyclovir after penetrating keratoplasty (PK) for herpes simplex virus (HSV) keratitis on recurrence, rejection, and graft failure rates. METHODS:Records from 70 consecutive patients who underwent PK for HSV keratitis at the W.K. Kellogg Eye Center be...

journal_title：Cornea

authors： Garcia DD,Farjo Q,Musch DC,Sugar A

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To study the corneal biocompatibility of bevacizumab on various cultured human corneal cells. METHODS:Cell cultures of corneal keratinocytes (CKs), corneal fibroblasts (CFs), and corneal endothelial cells (CECs) were harvested from human donor eyes and exposed to various concentrations of bevacizumab (0.25-5.0...

journal_title：Cornea

authors： Yoeruek E,Spitzer MS,Tatar O,Aisenbrey S,Bartz-Schmidt KU,Szurman P

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To describe an invasive spindle cell carcinoma of the conjunctiva managed by full-thickness eye wall resection. METHODS:A 51-year-old man developed a conjunctival mass that was excised and proved to be a spindle cell carcinoma. A tumor recurrence 20 months later was evaluated by ultrasound biomicroscopy (UBM) ...

journal_title：Cornea

authors： Shields JA,Eagle RC,Marr BP,Shields CL,Grossniklaus HE,Stulting RD

更新日期：2007-09-01 00:00:00

abstract：PURPOSE:To examine the cornea of patients with Marfan syndrome in comparison with a control group by using the in vivo confocal microscope. METHODS:Twenty-four eyes of 12 patients with Marfan syndrome had their corneas examined using the in vivo confocal microscope Heidelberg Retina Tomograph (HRT) II/Rostock Cornea M...

journal_title：Cornea

authors： Iordanidou V,Sultan G,Boileau C,Raphael M,Baudouin C,Marfan Study Group.

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:To study the expression of toll-like receptors (TLRs) in healthy corneas and corneas with active or nonactive herpetic stromal keratitis (HSK). METHODS:Eight corneas with HSK (including 5 active and 3 nonactive cases) and 8 healthy corneas were evaluated for TLR1-10 mRNA by reverse transcription-polymerase cha...

journal_title：Cornea

authors： Jin X,Qin Q,Chen W,Qu J

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:To report a case of interface infection by Candida albicans after deep anterior lamellar keratoplasty (DALK). METHODS:A 30-year-old man with keratoconus underwent DALK. Four weeks after surgery, the patient developed multiple infiltrates in the graft-host interface with absence of intraocular infection. Donor ...

journal_title：Cornea

authors： Fontana L,Parente G,Di Pede B,Tassinari G

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:To retrospectively evaluate the coexistence of congenital glaucoma with congenital hereditary endothelial dystrophy. METHODS:Ten infants presented to our hospital with diffuse corneal edema and bilaterally elevated intraocular pressure (IOP). These patients were diagnosed with congenital glaucoma. All patients...

journal_title：Cornea

authors： Ramamurthy B,Sachdeva V,Mandal AK,Vemuganti GK,Garg P,Sangwan VS

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:To report a recent significant increase of the number of patients diagnosed with Acanthamoeba keratitis (AK) at Wills Eye Hospital between 2004 and 2005. To determine the risk factors, clinical characteristics, treatments, and outcomes of patients with AK. METHODS:Retrospective consecutive case series of 20 ey...

journal_title：Cornea

authors： Thebpatiphat N,Hammersmith KM,Rocha FN,Rapuano CJ,Ayres BD,Laibson PR,Eagle RC Jr,Cohen EJ

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:The purpose of this report was to describe an uncommon wavelike epitheliopathy after phacoemulsification in a 59-year-old man with well-controlled diabetes mellitus. METHODS:Retrospective case report. RESULTS:A 59-year-old man with a history of well-controlled diabetes mellitus presented to us with irritation...

journal_title：Cornea

authors： Babu K,Narasimha Murthy K,Ramachandra Murthy K

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:To compare the frequency of positive rim cultures after penetrating keratoplasty using corneas preserved by hypothermic and organ culture storage. To evaluate the influence of standard procurement techniques on the frequency of microbial donor rim contamination. METHODS:Six hundred four donor corneas stored at...

journal_title：Cornea

authors： Fontana L,Errani PG,Zerbinati A,Musacchi Y,Di Pede B,Tassinari G

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To compare the rate of epithelial healing of corneal erosion in an animal model with 2 commercial formulations of fourth-generation fluoroquinolones: 0.3% gatifloxacin and 0.5% moxifloxacin. METHODS:Corneal erosions, 6 mm in diameter, were created in 28 rabbit eyes. The rabbits were randomized to receive topic...

journal_title：Cornea

authors： Barequet IS,Habot-Wilner Z,Lavinsky F,Ziv H,Belkin M,Rosner M

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To report a case of recurrent herpes simplex virus (HSV) epithelial keratitis after intravitreal triamcinolone acetonide injection for the treatment of diabetic macular edema. METHODS:Case report. RESULTS:We describe a case of a 59-year-old woman with a history of ocular HSV disease and severe proliferative d...

journal_title：Cornea

authors： Shtein RM,Stahl RM,Saxe SJ,Mian SI

更新日期：2007-06-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of supratarsal triamcinolone injection in the treatment of superior limbic keratoconjunctivitis (SLK). METHODS:Forty eyes of 20 patients were diagnosed with SLK. All eyes with long-standing severe ocular irritation unresponsive to topical steroid and artificial tears were treated with ...

journal_title：Cornea

authors： Shen YC,Wang CY,Tsai HY,Lee YF

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:To document the relationship of iris cavernous hemangiomas with multiorgan hemangiomas in a child. METHODS:A 7-year-old girl with kidney hemangiomas, brain hemangiomas, and skin hemangiomas developed blurred vision and darkening of the right iris. She had undergone 6 previous brain surgeries and multiple revis...

journal_title：Cornea

authors： Thangappan A,Shields CL,Dinowitz M,Shields JA

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:To verify the possibility of using a commercially available ophthalmologic white light confocal microscope for imaging optical sections of donated corneas preserved at 4 degrees C, especially for endothelial evaluation. METHODS:Sixteen corneas donated to the Warsaw Eye Bank but excluded from use in surgery for...

journal_title：Cornea

authors： Szaflik JP

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:Young children are prone to develop amblyopia after penetrating injury. We sought to evaluate the management of penetrating corneal injury without intraocular foreign body (IOFB) in children

journal_title：Cornea

authors： Segev F,Assia EI,Harizman N,Barequet I,Almer Z,Raz J,Moisseiev J

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:To describe 3-dimensional optical coherence tomography (OCT) findings in a case of granular corneal dystrophy. METHODS:A 1310-nm high-speed swept-source OCT prototype was used to image the 3-dimensional structures of the cornea of a patient with granular corneal dystrophy. RESULTS:Three-dimensional OCT clearl...

journal_title：Cornea

authors： Miura M,Mori H,Watanabe Y,Usui M,Kawana K,Oshika T,Yatagai T,Yasuno Y

更新日期：2007-04-01 00:00:00

abstract：PURPOSE:To report clinical outcome of treating ocular demodecosis by lid scrub with tea tree oil (TTO). METHODS:Retrospective review of clinical results in 11 patients with ocular Demodex who received weekly lid scrub with 50% TTO combined with daily lid hygiene with tea tree shampoo. RESULTS:These 11 patients also h...

journal_title：Cornea

authors： Gao YY,Di Pascuale MA,Elizondo A,Tseng SC

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:To compare optical low-coherence reflectometry (OLCR) and ultrasound pachymetry in measuring corneal graft thickness in patients after keratoplasty. METHODS:We retrospectively measured the central graft thickness in 41 eyes of 41 patients with the OLCR pachymeter (Haag Streit, Koeniz, Switzerland) and the SP-2...

journal_title：Cornea

authors： Gaujoux T,Borderie VM,Yousfi H,Bourcier T,Touzeau O,Laroche L

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:To report the use of anterior stromal micropuncture and amniotic membrane transplantation in the management of painful bullous keratopathy in patients with poor visual potential. METHODS:Interventional case series. A retrospective review was performed to identify all patients who were treated by one of us (A.J...

journal_title：Cornea

authors： Sonmez B,Kim BT,Aldave AJ

更新日期：2007-02-01 00:00:00

abstract：PURPOSE:To determine whether a combination of early amniotic membrane transplantation (AMT) and early topical corticosteroid treatment could be a safe adjuvant therapy during antibacterial treatment in severe bacterial keratitis (BK) for relieving pain, avoiding iatrogenic epithelial toxicity, and allowing earlier use ...

journal_title：Cornea

authors： Gicquel JJ,Bejjani RA,Ellies P,Mercié M,Dighiero P

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:To describe the clinical and in vivo confocal microscopic findings of the cornea in 2 male siblings with Maroteaux-Lamy syndrome. METHODS:Two male siblings 27 and 22 years of age who had been diagnosed with Maroteaux-Lamy syndrome underwent ophthalmologic assessment. In vivo confocal microscopy of their cornea...

journal_title：Cornea

authors： Mocan MC,Eldem B,Irkec M

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:Comparison of corneal pachymetry assessment with ultrasound and Orbscan II using acoustic factor and subtraction methods. METHODS:Ultrasound and Orbscan pachymetry for all patients with LASIK performed between July 2002 and May 2003 were retrospectively analyzed. Comparison between the 2 preoperative measureme...

journal_title：Cornea

authors： Cheng AC,Tang E,Mohamed S,Lam DS

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:To analyze factors implicating the association of ReNu with MoistureLoc (ReNu ML) multipurpose contact lens solution (MPS) with the increased incidence of Fusarium keratitis. METHODS:Used contact lens cases with and without contact lenses and MPS containers were collected from patients with confirmed or possib...

journal_title：Cornea

authors： Zhang S,Ahearn DG,Noble-Wang JA,Stulting RD,Schwam BL,Simmons RB,Pierce GE,Crow SA Jr

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:To report a case of infectious crystalline keratopathy caused by Gemella haemolysans. METHODS:Observational case report. A 65-year-old woman underwent penetrating keratoplasty for contact lens-related Acanthamoeba keratitis and developed a nonhealing epithelial defect. Despite continued prophylaxis with topica...

journal_title：Cornea

authors： Elmallah MK,Munir WM,Janda WM,Tu EY

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:This review discusses cellular senescence, the state in which normal cells do not respond to growth stimuli, and shows characteristic alterations in their cytologic and biochemical properties and their gene expression profiles. METHODS AND RESULTS:Cellular senescence is elicited by various stresses. It was rec...

journal_title：Cornea

authors： Ishikawa F

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:Light reflex from the cornea and tear film as contributors to beautiful eyes ("eye sparkling") are reviewed. METHODS:A systematic literature review was conducted using "Purkinje-Sanson image," "corneal light reflex," "corneal topography," "corneal wavefront aberration," and "tear interference image" as search ...

journal_title：Cornea

authors： Goto E

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:To assess the endothelial cell loss after cataract extraction using a fluid-based system and compare it with conventional ultrasound. METHODS:A total of 46 eyes of 23 patients with up to 3+ bilateral cataract were included. The first eye was randomized to either fluid-based system or conventional ultrasound, a...

journal_title：Cornea

authors： Sandoval HP,de Castro LE,Vroman DT,Solomon KD

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:To evaluate the feasibility and cut quality of corneal trephination in human donor corneal tissue with the femtosecond laser. METHODS:Twelve human corneoscleral discs were inserted in an artificial anterior chamber. After corneal thickness measurement and tonometry, the cornea was mounted on a femtosecond lase...

journal_title：Cornea

authors： Meltendorf C,Schroeter J,Bug R,Kohnen T,Deller T

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:To describe a case of conjunctival malignant melanoma associated with pseudomelanomatous alteration of the apposing tarsal conjunctiva. METHODS:A 93-year-old woman presented with an elevated, pigmented mass on her superior bulbar conjunctiva. The tumor was associated with increased pigmentation of the apposing...

journal_title：Cornea

authors： Reddy S,Finger PT,Kurli M,Bui A,Iacob CE

更新日期：2006-10-01 00:00:00

abstract：PURPOSE:To report the histopathologic findings in the host tissue of 2 human keratoconic corneas undergoing maximum-depth anterior lamellar keratoplasty (MDALK) using the manual dissection technique described by Melles. METHODS:Corneal buttons were examined from 2 patients with keratoconus who underwent MDALK using th...

journal_title：Cornea

authors： Saw VP,Ng T,Crouch R,Maloof AJ

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:To report the clinical results of posterior lamellar keratoplasty (PLK) using predissected organ-cultured donor corneal tissue implanted after stripping of the Descemet membrane. METHODS:Twenty-two eyes of 22 patients in whom a PLK procedure was performed for pseudophakic bullous keratopathy and/or Fuchs endot...

journal_title：Cornea

authors： Nieuwendaal CP,Lapid-Gortzak R,van der Meulen IJ,Melles GJ

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:To report spontaneous corneal perforation as a presenting sign of unilateral Terrien marginal degeneration in a young adult. METHODS:A 19-year-old woman presented with sudden loss of vision in her left eye of 1-day duration. Examination revealed superior corneal thinning with superficial vascularization and se...

journal_title：Cornea

authors： Srinivasan S,Murphy CC,Fisher AC,Freeman LB,Kaye SB

更新日期：2006-09-01 00:00:00

abstract：PURPOSE:Diabetes is accompanied by an increased autofluorescence of the cornea, probably because of accumulation of advanced glycation end products (AGEs). The pathogenic mechanism is still unknown. This study aimed to quantify differences in corneal cell densities between diabetic patients and healthy controls. METHO...

journal_title：Cornea

authors： Quadrado MJ,Popper M,Morgado AM,Murta JN,Van Best JA

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:To determine how ocular surface epithelium adjusts to an increase in cell replication after treatment with the opioid antagonist naltrexone (NTX). METHODS:Adult male rats were given twice daily injections of 30 mg/kg NTX or vehicle for 7 days. Outcomes of NTX administration included DNA synthesis (monitored wi...

journal_title：Cornea

authors： Zagon IS,Sassani JW,McLaughlin PJ

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:To report a case of ocular manifestations after a primary varicella infection. METHODS:Review of the literature and a case report of a 10-year-old male patient with history of blurry vision and an enlarged pupil 2 months after a varicella infection. Examination revealed uveitis, interstitial keratitis, and int...

journal_title：Cornea

authors： Fernández de Castro LE,Sarraf OA,Hawthorne KM,Solomon KD,Vroman DT

更新日期：2006-08-01 00:00:00

abstract：PURPOSE:To evaluate the safety, validity, and comfort of 0.35% fluorexon disodium and 0.4% benoxinate (Flura-Safe) compared with the gold standard of 0.25% sodium fluorescein and 0.4% benoxinate for Goldmann applanation tonometry (GAT). METHODS:This was a double-masked, randomized, crossover clinical trial. Subjects r...

journal_title：Cornea

authors： Ng LT,Tong JW,De Land PN

更新日期：2006-07-01 00:00:00

abstract：PURPOSE:To report clinical, in vivo confocal microscopy and ex vivo histopathologic findings of Salzmann nodular degeneration (SND). METHODS:A 48-year-old woman with symptoms of ocular irritation and decreased visual acuity caused by SND in both eyes was treated by corneal scraping and phototherapeutic keratectomy (PT...

journal_title：Cornea

authors： Meltendorf C,Bühren J,Bug R,Ohrloff C,Kohnen T

更新日期：2006-07-01 00:00:00

abstract：PURPOSE:To describe the incidence and prevalence of glaucoma in a patient population with severe ocular surface disease (OSD). METHODS:A retrospective case series was compiled from all charts of patients in the Cincinnati Eye Institute/University of Cincinnati and University of Minnesota population with a diagnosis of...

journal_title：Cornea

authors： Tsai JH,Derby E,Holland EJ,Khatana AK

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:To develop a rat model of chronic Acanthamoeba polyphaga keratitis suitable for pharmacologic assessment of therapeutic agents. METHODS:An A. polyphaga isolate (ATCC #50495) was grown in peptone-yeast extract-glucose medium. Five-weeks-old, Sprague-Dawley male rats were injected with 10(3) or 10(4) trophozoite...

journal_title：Cornea

authors： Vasseneix C,Gargala G,François A,Hellot MF,Duclos C,Muraine M,Benichou J,Ballet JJ,Brasseur G,Favennec L

更新日期：2006-06-01 00:00:00